About Manchester CRF
“A world-class integrated Clinical Research Facility that enhances translation of scientific advances through experimental medicine research, and provides opportunities for people of all ages and backgrounds across Greater Manchester to take part in research”
Transforming the lives of people with cystic fibrosis: CF modulator therapies, from trial to patient.
Manchester CRF has been at the forefront of Cystic Fibrosis trials for almost a decade, and played a key role during a period that has seen rapid evolution of life-changing therapies, including trials of the most recent and most powerful triple combination therapies
Manchester CRF was asked to facilitate the fast-track opening and provide vital support to the Public Health England (PHE) ESCAPE (Enhanced Seroprevalence for COVID-19 Antibodies) study which aimed to better understand the spread of coronavirus by monitoring the development of and changes in antibodies linked to COVID-19 – the only NHS site to take part in the study.
Manchester Clinical Research Facility (MCRF), Manchester University NHS Foundation Trust (MFT) and the University of Manchester (UoM) have created a strategic partnership with AvroBio – a Massachusetts-based biotechnology company focused on delivering step-change cell and gene therapies targeting cancer and rare disease – to trial a first-in-person ex vivo gene therapy treatment using lentiviral vector-modified stem cells at the MCRF at Royal Manchester Children’s Hospital.
Addressing health inequalities is a major strategic focus for Manchester Clinical Research Facility (MCRF), and public involvement in the design of clinical research can make a lasting impact in tacking these inequalities.
Be Part of Research
Research changes lives but it can only happen thanks to people who volunteer for studies. Whether you are living with a condition or simply want to make a difference you can help.
Manchester CRF is dedicated to providing opportunities for people of all ages and backgrounds to take part in, and helps shape and design, clinical research.