About Manchester CRF

Our Vision

“A world-class integrated Clinical Research Facility that enhances translation of scientific advances through experimental medicine research, and provides opportunities for people of all ages and backgrounds across Greater Manchester to take part in research”


About Us

ESCAPE: study of COVID-19 seroprevalence

Manchester CRF was asked to facilitate the fast-track opening and provide vital support to the Public Health England (PHE) ESCAPE (Enhanced Seroprevalence for COVID-19 Antibodies) study which aimed to better understand the spread of coronavirus by monitoring the development of and changes in antibodies linked to COVID-19 – the only NHS site to take part in the study.

Strategic partnerships: AvroBio

Manchester Clinical Research Facility (MCRF), Manchester University NHS Foundation Trust (MFT) and the University of Manchester (UoM) have created a strategic partnership with AvroBio – a Massachusetts-based biotechnology company focused on delivering step-change cell and gene therapies targeting cancer and rare disease – to trial a first-in-person ex vivo gene therapy treatment using lentiviral vector-modified stem cells at the MCRF at Royal Manchester Children’s Hospital.

Be Part of Research

Research changes lives but it can only happen thanks to people who volunteer for studies. Whether you are living with a condition or simply want to make a difference you can help.

Manchester CRF is dedicated to providing opportunities for people of all ages and backgrounds to take part in, and helps shape and design, clinical research.


Find Out More