The success of Manchester Clinical Research Facility is based on the impact we make to the lives of our patients, their families, and our communities.

Read the stories below to find out more about how our clinical research is changing treatment, experiences, and outcomes for our patients and participants.

ESCAPE: study of COVID-19 seroprevalence

Manchester CRF was asked to facilitate the fast-track opening and provide vital support to the Public Health England (PHE) ESCAPE (Enhanced Seroprevalence for COVID-19 Antibodies) study which aimed to better understand the spread of coronavirus by monitoring the development of and changes in antibodies linked to COVID-19 – the only NHS site to take part in the study.

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Strategic partnerships: AvroBio

Manchester Clinical Research Facility (MCRF), Manchester University NHS Foundation Trust (MFT) and the University of Manchester (UoM) have created a strategic partnership with AvroBio – a Massachusetts-based biotechnology company focused on delivering step-change cell and gene therapies targeting cancer and rare disease – to trial a first-in-person ex vivo gene therapy treatment using lentiviral vector-modified stem cells at the MCRF at Royal Manchester Children’s Hospital.

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