Cancer therapy with potential to transform lupus treatment delivered in Manchester in UK first
Friday 8 November 2024
A woman in Manchester is the first person in the UK to receive an innovative treatment for the most serious form of lupus – an autoimmune condition which can cause damage to the heart, lungs, joints, brain or kidneys.
Cancer Research UK announces dosing of first patient in first in-human-trial with UCB4594 therapy
Wednesday 30 October 2024
Cancer Research UK are pleased to announce that the first patient has received treatment in a clinical trial for people with advanced cancers. The first site for the study has opened at the NIHR Manchester CRF at The Christie NHS Foundation Trust in Manchester.
Two trials help mum with metastatic breast cancer on the road to recovery
Wednesday 9 October 2024
A mum of two from Altrincham in Greater Manchester with breast cancer has seen her tumours decrease by 65% thanks to research at The Christie NHS Foundation Trust in Manchester.
Celebrating my culture during the Black History Month 2024 – A blog by Maggie Amegadzie
Tuesday 8 October 2024
In celebration of BHM 2024, Maggie Amegadzie, Senior Paediatric Clinical Research Nurse at the NIHR Manchester CRF at Royal Manchester Children’s Hospital shares why she is proud of her heritage and career caring for children and young people.
MAHSC Inaugural Lecture: Professor Raja Padidela and Professor Benjamin Parker
Monday 7 October 2024
MAHSC Honorary Clinical Chairs are celebrated as we invite the audience to hear their professional and personal journeys, clinical and research areas, and plans for the future. This MAHSC Inaugural Lecture welcomed MAHSC Honorary Clinical Chairs Professor Raja Padidela and Professor Benjamin Parker.
New Cystic Fibrosis Innovation Hub in Manchester to develop pioneering tests and treatments for lung infections
Tuesday 1 October 2024
Researchers at The University of Manchester in collaboration with Manchester University NHS Foundation Trust (MFT) are launching a new Cystic Fibrosis Innovation Hub to accelerate the development of new tests and treatment approaches for lung infections, and improve the way that lung health for people with Cystic Fibrosis is managed in the UK.
#Red4Research Blog: Liz Worsley, Nurse Manager NIHR Manchester CRF at RMCH
Friday 20 September 2024
To celebrate this year’s #Red4Research Day, Nurse Manager at the NIHR Manchester Clinical Research Facility at Royal Manchester Children’s HospitaL Liz Worsley, shares her research journey and why she is proud to be part of research that is changing lives for the better.
Low dose morphine shows promise as effective treatment for chronic cough in people with idiopathic pulmonary fibrosis
Thursday 19 September 2024
Low dose morphine could treat chronic cough in people with idiopathic pulmonary fibrosis, research from across 3 National Institute for Health and Care Research (NIHR) Clinical Research Facilities has shown.
Pre-operative immunotherapy trial could improve outcomes for some bowel cancer patients
Friday 12 July 2024
An immunotherapy drug trialled at The Christie which is given before surgery, instead of the standard treatment of surgery and chemotherapy, meant that more than ten times more patients with a certain genetic profile were cancer free after surgery, according to early clinical trial results.
A new drug being trialled at The Christie NHS Foundation Trust in Manchester could be a breakthrough for patients with a hard-to-treat form of leukaemia
Tuesday 03 May 2024
A new drug being trialled at The Christie NHS Foundation Trust in Manchester could be a breakthrough for patients with a hard-to-treat form of leukaemia.
Food poisoning led to rare cancer discovery for Wigan man
Friday 03 May 2024
A railway worker from Wigan, who discovered he had terminal cancer after suffering a bout of food poisoning, feared he wouldn’t see his eldest daughter get married or meet his fourth grandchild. However, thanks to taking part in research at The Christie NHS Foundation Trust in Manchester, he has lived to do both.
Wallasey woman defies the odds thanks to new drug trial
Tuesday 19 March 2024
A woman from Wallasey in Merseyside with Non Hodgkin’s lymphoma, who has only previously been in remission for a month in the past eight years, is enjoying life thanks to daily trial drug capsules which have cleared her of cancer.
Pioneering study looks at new vaccines to help limit future global flu pandemics
Monday 12 February 2024
Researchers at Northern Care Alliance NHS Foundation Trust are supporting a pioneering study for new vaccines that could help limit future global influenza pandemics.
Sheffield woman celebrates six years of successful experimental bowel cancer treatment
Thursday 8 February 2024
Sara Anne Morley, a 58-year-old grandmother from Sheffield has stage four bowel cancer, the most advanced kind. After exhausting all the standard treatment options available to her, she started on an early phase clinical trial at The Christie NHS Foundation Trust in Manchester in early 2018.
Research team at NIHR Manchester CRF recruits first patient to device study to help reduce side effects from dialysis treatment
Wednesday 7 February 2024
The first patient has been recruited to a new device study which aims to improve dialysis treatment by preventing side effects for kidney disease patients.
Manchester babies play crucial role in research which shows an 83 per cent drop in hospital admissions for winter virus
Tuesday 6 February 2024
Babies at Manchester University NHS Foundation Trust (MFT) have been part of groundbreaking research which has found that a single dose of a treatment for a respiratory infection in infants can help cut hospital admissions by more than 80 per cent.
Woman struck twice with tonsil cancer sees tumours shrink on clinical trial
Tuesday 2 January 2024
A woman with head and neck cancer has seen her tumours shrink by a third thanks to a clinical trial at the Christie NHS Foundation Trust in Manchester.
Your Path in Research – A blog by Kathryn Slevin
Monday 4 December 2023
Kathryn Slevin, Research Delivery Lead at the NIHR Manchester Clinical Research Facility at Salford Royal Hospital, shares her experience working within research at the NHS.
Manchester research leads to NHS roll out of life-saving treatment for babies with rare disease
Monday 27 November 2023
Babies and toddlers with a rare and fatal genetic condition can now receive life-saving treatment on the NHS for the first time following clinical research studies first carried out at the Manchester Clinical Research Facility at Royal Manchester Children’s Hospital (RMCH).
First patient in UK treated with pioneering new gene therapy for Gaucher disease
Wednesday 25 October 2023
The first patient in the UK has been treated with a pioneering new investigational gene therapy designed to treat the debilitating genetic disorder Gaucher disease.
Onam festival celebrations held at the NIHR Manchester CRF at Manchester Royal Infirmary
Wednesday 25 October 2023
In honour of the festival of Onam, a special celebration was held to mark the occasion by colleagues at the National Institute for Health and Care Research (NIHR) Manchester Clinical Research Facility at Manchester Royal Infirmary (MRI).
Lancashire man’s aggressive prostate cancer now close to undetectable thanks to a new drug trial at The Christie
Sunday 22 October 2023
A Lancashire man whose aggressive prostate cancer was rapidly progressing through standard therapies has now been told that his cancer is close to undetectable after just four months of being on a first-in-human trial at The Christie NHS Foundation Trust.
Celebrating 10 years of research for Huntington’s disease at MFT
Friday 15 September 2023
A special event took place at Manchester Clinical Research Facility (CRF) at Manchester Royal Infirmary (MRI) to celebrate 10 years of MFT’s involvement in ‘Enroll-HD’ – a global registry study for Huntington’s disease (HD).
‘A better day, every day,’ working together to transform lives through research – World Duchenne Awareness Day
Thursday 7 September 2023
For a nine-year old boy and his family, being part of Duchenne Muscular Dystrophy clinical research at NIHR Manchester CRF at Royal Manchester Children’s Hospital has been ‘amazing,’ for many reasons.
Manchester CRF colleagues named MAHSC Honorary Clinical Chairs
Thursday 31 August 2023
Two clinicians from the National Institute for Health and Care Research (NIHR) Manchester Clinical Research Facility (CRF) are among 15 outstanding individuals announced today by Manchester Academic Health Science Centre (MAHSC), part of Health Innovation Manchester, as Honorary Clinical Chairs for 2023.
Blood cancer trial gives former nurse new hope
Tuesday 22 August 2023
A former NHS nurse, who was diagnosed with cancer three years ago is now in complete remission thanks to a ground-breaking new blood cancer drug she is receiving at The Christie NHS Foundation Trust.
Disturbed sleep may partially explain Long COVID breathlessness, find researchers
A major UK study has discovered that the disturbed sleep patterns in patients hospitalised with COVID-19 was likely to be a driver of breathlessness.
NIHR IMID BioResource recruits its 10,000th volunteer in major milestone
The platform for research into Immune-Mediated Inflammatory Diseases (IMIDs) has now signed up 10,000 participants nationwide. Find out about the value of having such a large cohort and what it means for future research studies into IMIDs.
Cutting-edge research in Greater Manchester receives funding boost from NIHR
The National Institute for Health and Care Research (NIHR) has awarded more than £96 million to 93 NHS organisations as part of a capital investment.
Senior Paediatric Clinical Research Nurse completes Windrush Leadership Programme
Congratulations to Senior Clinical Research Nurse, Margretha Amegadzie, who has successfully completed the Windrush Nurses and Midwives Leadership Programme.
Launch event marks multi-million-pound investment into research across Greater Manchester, Lancashire and South Cumbria
The Mayor of Greater Manchester, Andy Burnham, officially opened a successful launch event to celebrate the multi-million-pound funding boost for the NIHR Manchester Biomedical Research Centre (BRC) and NIHR Manchester Clinical Research Facility (CRF).
Researchers pioneer study for rare genetic condition myotonic dystrophy type 1
Thursday 18 May 2023
Researchers in Salford are pioneering a study examining a potential new treatment for people with a rare and currently incurable genetic condition.
Christie patient injected with cancer-killing virus
Wednesday 5 April 2023
A new type of cancer therapy described by medics as a ‘marvel of genetic engineering’ is showing promising results in an early clinical trial.
Christie lung cancer trial leads to game-changer drug available on NHS
Wednesday 22 March 2023
Clinical trial shows new anti-cancer tablet is a better alternative to chemotherapy.
Malfunctioning immune cell behaviour could be drug target in Long Covid
Thursday 16 March 2023
Greater Manchester researchers have shown for the first time that malfunctioning behaviour of a type of immune cell is linked to specific symptoms of long COVID.
First participant in new study to evaluate next generation COVID-19 protection encourages others to be part of research
Tuesday 7 March 2023
The world’s first participant in a new COVID-19 trial taking place at Manchester University NHS Foundation Trust (MFT), is part of research that may provide important protection for people with a weakened immune system.
Christie cancer trial improves outcome for men with hard-to-treat prostate cancer
Wednesday 1 March 2023
A new treatment for prostate cancer trialled at The Christie NHS Foundation Trust in Manchester has shown to be more effective for the hardest to treat form of the disease.
Setting new challenges – a blog by Sue Stockdale, Advanced Nurse Practitioner
Wednesday 1 March 2023
Sue Stockdale, a newly qualified Trainee Advanced Nurse Practitioner (ANP) at NIHR Manchester Clinical Research Facility (CRF) at Wythenshawe Hospital, shares insights into her research journey and ambitions for her new role.
Research, an opportunity not to be missed – A blog by Dr Shiva Pandey
In his blog, Dr Shiva Pandey shares why he is encouraging other junior doctors to consider research as an opportunity not to be missed.
International Nurses Day 2022 – My journey to becoming a Clinical Research Nurse, by Joshi Prabhu
On International Nurses Day 2022, Clinical Research Nurse Joshi Prabhu shares her nursing journey and why she’s passionate about research.
Trials carried out at MFT show drug eases symptoms of chronic cough
The results of the world’s first Phase 3 trials, of a new drug Gefapixant, show that it can ease the often distressing symptoms of chronic cough, with minimal side effects.
New funding boost for delivery of early stage clinical research across Greater Manchester
The MFT-hosted NIHR Manchester Clinical Research Facility (MCRF) has received a £15.5 million award, widening opportunities for people across Greater Manchester to participate in research.
Why, as a new Clinical Research Nurse, I am encouraging student nurses to follow a path into research
In her blog Gabby Addison shares her student nurse experiences at the NIHR Manchester Clinical Research Facility, and how she is proud to be back as a Clinical Research Nurse.
Early data for multivariant COVID-19 vaccine booster shows promise
The first results of an early trial of a multi-variant COVID-19 vaccine booster, launched in Manchester in September 2021, has shown it is driving a comprehensive immune response.
Manchester researchers and patients contribute to study showing people with long COVID after hospitalisation face limited recovery after one year
People who were hospitalised with COVID-19 and continued to experience symptoms at five months show limited further recovery one year after hospital discharge, according to latest research.